FormuMax Scientific
 
ÀÛ¼ºÀÏ : 14-12-12
[FormuMax Scientific] Doxoves¢â - Liposomal Doxorubicin HCl, New 2mg/mL

 

Doxoves¢â - Liposomal Doxorubicin HCl, New 2mg/mL

 

 

Ç×Á¾¾ç Ȱ¼ºÀ» °®´Â Ç×»ý¹°Áú Doxorubicin HClÀ» ³»Æ÷ÇÑ liposomeÀÔ´Ï´Ù. Doxorubicin HClÀ» liposome ³»¿¡ ³»Æ÷

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ÀÔ°æÀÌ ±ÕÀÏÇϱ⠶§¹®¿¡ lot °£ÀÇ Â÷À̰¡ ÀûÀº °íǰÁú·Î¼­, ³ôÀº ºÀÀÔ È¿À²À» º¸À̵µ·Ï Á¶Á¦µÇ¾î ÀÖ½À´Ï´Ù.

Doxorubicin HClÀÌ ¾ø´Â control¿ë liposomeµµ ÀÖ½À´Ï´Ù.

* DoxorubicinÀº, reverse transcriptase, RNA polymeraseÀÇ È°¼ºÀ» ¾ïÁ¦ÇÏ´Â Ç×»ý¹°ÁúÀÔ´Ï´Ù. Intercalation¿¡

ÀÇÇØ ÀÌÁß °¡´Ú DNA¿¡ °áÇÕÇÏ¿©, DNAÀÇ º¹Á¦¡¤Àü»ç¸¦ ¾ïÁ¦ÇÏ´Â °ÍÀ¸·Î »ý°¢µÇ°í ÀÖÀ¸¸ç, ¼¼Æ÷ »ç¸êÀ» À¯µµÇÕ´Ï´Ù.

 

 

Cryo-EM of FormuMax's liposome doxorubicin HCl (F30204B-D) (Image taken by NanoImaging Services Inc.)

 

 

FormuMax has been providing custom-made formulations of liposomal doxorubicin HCl with various lipid

compositions and particle sizes. There has been an increased demand of liposomal doxorubicin

comparable to the commercial Doxil¢ç. Now we are proudly naming our product, Doxoves¢ç, and making it

available to you at an affordable price.

 

Doxoves¢çis manufactured to high quality with consistent lot-lot characteristics, tight particle size distribution

and high drug encapsulation efficiency.  A high drug concentration of 4.0 mg/mL (40mM lipid) allows

researchers to perform experiments athigher concentrations/doses. Doxoves¢ç is comparable to the

commercial product Doxil¢ç in characteristics, stability and pharmacokinetics. Cryo-TEM studies  have

shown that the encapsulated doxorubicin forms the same type of rod-like structures as in Doxil¢ç. A recent

PK study of two batches of Doxoves¢ç demonstrated an excellent PK profile with t1/2 of 30-40hr similar to that

of Doxil¢ç.

 

  

 

Good News !!!   

According to request from customers, the 2.0mg/mL liposomal doxorubicin HCl is now available.

 

 


Ordering informations


Catalog No.

Product Name

Size

F30204C-D

Combo kit of Doxoves¢ç and the plain control liposomes

2 ml & 10 ml

F30204B-C

Control liposomes for Doxoves¢ç (4.0mg/mL)

2 ml & 10 ml

F30204B-C2

Control liposomes for Doxoves¢ç (2.0mg/mL)

2 ml & 10 ml

F30204B-D

Doxoves¢ç - STEALTH Liposomal Doxorubicin HCl (4.0mg/mL)

2 ml & 10 ml

F30204B-D2

Doxoves¢ç - STEALTH Liposomal Doxorubicin HCl (2.0mg/mL)

2 ml & 10 ml

FB30020

Dilution Buffer for Doxoves¢â

2 ml & 10 ml

 

 


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