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작성일 : 19-11-20
[Immudex ApS] EBV Dextramer Package 1

 

Dextramer Packages, EBV Dextramer® Package 1

Detecting EBV-specific immunity

 

Activation of CD8+ T cells specific for persistent and acute viral infection is central in human anti-viral

immunity. Epstein-Barr virus (EBV) is a persistent virus that infects 90% of the human population. Primary

infection may cause acute infectious mononucleosis and persistent infection may be associated with the

development of several malignancies. CD8+ T cells play a critical role in controlling both the primary and

persistent phases of infection.

 

Features

• Accurate quantification of  EBV-specific T cells

• Includes multiple alleles

• Specific, sensitive, reproducible

• Applicable on blood, HPBMC, tissue sections

 

Applications

The EBV Dextramer Package 1 is useful for detection and isolation of EBV-specific CD8+ T cells in a variety

of applications:

• Monitoring EBV immune status in immune-compromised individuals

• Monitoring EBV immune status following transplantation

• Testing of EBV-specific vaccines

• Profiling of EBV-specific T cell responses

 

The EBV Dextramer Package consists of Dextramer reagents displaying epitopes from immunodominant EBV

antigens. The Package also includes a negative control Dextramer.

 

 Kit components

   

 Catalog No.

 Dextramer

 Antigen

Size

 WB2130

 HLA-A*0201 / GLCTLVAML

 BMLF-1

50 tests

 WK2145

 HLA-B*3501 / HPVGEADYFEY

 EBNA-1

50 tests

 WH2166

 HLA-B*0702 / RPPIFIRRL

 EBNA-3A

50 tests

 WI2147

 HLA-B*0801 / FLRGRAYGL

 EBNA-3A

50 tests

 NI3233

 General / Negative Control

 -

50 tests

 

Related products

The EBV Dextramer reagents in the EBV Dextramer Package 1 are also available as single reagents.

Additional EBV-specific Dextramer reagents not provided in EBV Dextramer Package 1 are available.

For further information search for EBV Dextramer reagents in the product database.

 

  

Ordering information

    

Catalog No.

Product Name

Size

RX05-PE, -APC, -FITC

EBV Dextramer® Package 1

50 tests each

 

 

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