products
 
작성일 : 22-04-21
[Iris Biotech] Permanent Linkers, Photoactivatable Linkers

 

Permanent Linkers, Photoactivatable Linkers

 

Irradiation of diazirines with UV light (ca. 350-360 nm) yields a highly reactive carbene species that can

undergo insertions into C–C, C–H, O–H, and X–H (X = heteroatom) bonds of neighboring molecules to

irreversibly form a covalent bond (Fig. 1). The diazirine moiety is the smallest of all photophores, so

introduction of a diazirine-bearing amino acid into a peptide or protein usually does not impair its biological

activity. Further advantages of diazirine crosslinkers are their stability at room temperature and their relative

stability against nucleophiles as well as towards both acidic and basic conditions.

 클릭하시면 닫힙니다.이미지 저장을 원하시면 마우스 오른쪽클릭후 '다른이름으로 저장'을 하세요

Fig. 1: Use of photo-phenylalanine for the identification of angiotensin-II receptor binding sites; 125I is used

as a radiotracer.

 

Photo-Ethylamine*HCl

Chemical name:

 

2-(3-methyl-3H-diazirin-3-yl)ethan-1-amine hydrochloride

Cas-no.:

 

25055-95-2

Formula:

 

C4H9N3*HCl

Molecular weight:

 

99.13*36.45 g/mol

 

 

 클릭하시면 닫힙니다.이미지 저장을 원하시면 마우스 오른쪽클릭후 '다른이름으로 저장'을 하세요

 

Photo-Benzoic acid  

Chemical name:

 

4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzoic acid

Cas-no.:

 

85559-46-2

Formula:

 

C9H5F3N2O2

Molecular weight:

 

230.14 g/mol

 

 

 클릭하시면 닫힙니다.이미지 저장을 원하시면 마우스 오른쪽클릭후 '다른이름으로 저장'을 하세요

 

Photo-Benzylamine*HCl

Chemical name:

 

4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzylamine hydrochloride

Cas-no.:

 

1258874-29-1

Formula:

 

C9H8N3F3*HCl

Molecular weight:

 

215.18*36.45 g/mol

 

 

 클릭하시면 닫힙니다.이미지 저장을 원하시면 마우스 오른쪽클릭후 '다른이름으로 저장'을 하세요

 

ATFB

Chemical name:

 

4-Azido-2,3,5,6-tetrafluorobenzoic acid

Cas-no.:

 

122590-77-6

Formula:

 

C7HF4N3O2

Molecular weight:

 

235.1 g/mol

 

 

 클릭하시면 닫힙니다.이미지 저장을 원하시면 마우스 오른쪽클릭후 '다른이름으로 저장'을 하세요

  

Ordering informations

    

Catalog No.

Product Name

Size

RL-2910

Photo-Ethylamine*HCl

250, 500mg & 1g

RL-2920

Photo-Benzoic acid

200g & 1g

RL-2930

Photo-Benzylamine*HCl

200g & 1g

RL-2035

ATFB

250, 500mg, 1 & 5g

 

 

▣ 관련 페이지 ; Iris Biotech GMBH