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작성일 : 22-04-25
[BroadPharm] Polymer PEG, Alkyne

 

Polymer PEG (Polydisperse PEG)

 

Polymer PEG is a Polyethylene glycol (PEG) polymer with an averaged molecular weight, such as 2K, 5K,

10K, 20K with PDI ranging from 1.01-1.10. Polymer PEG is also known as polydisperse PEG, or Poly-PEG.

There are different shapes of Polymer PEG, such as linear, Y-shaped, branched, or star shaped with

different PEG chain lengths as shown in Figure 1. PEG chain can be attached with different functional groups

for chemistry modification and industrial application.

 

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Figure 1. Examples of Polymer PEG that are commercially available. Typical functional groups include

Acrylate, alkyne, Amine, Azide, DBCO, TCO, Aldehyde, Acid, NHS ester, Hydrazide, Maleimide, Silane,

Biotin, Tos, or Thiol.

 

Polymer PEG have become especially attractive tools in various pharmaceutical, biological and chemical

industry application due to its aqueous solubility, high flexibility and non-immunogenicity

  

 

Polymer PEG, Alkyne

 

Alkyne-attached PEG polymer can react with azide group via Cu catalyzed click chemistry which generates

a stable triazole bond. The click chemistry has profound impacts on polymer and materials science,

chemical biology and drug discovery, bioimaging, and more.

 

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Propargyl-PEG-Mal

Catalog No.

Product Name

Size

Feature

Structure

BP-25839

Propargyl-PEG-Mal, MW 1,000

100, 250 & 500mg

Propargyl-PEG-Mal, MW 1,000 is a copper click chemistry PEGylation reagent containing a thiol reactive

maleimide group. The coupling between thiol and maleimide can be done easily at pH 6.5-7.5 in an

aqueous solution.

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BP-25840

Propargyl-PEG-Mal, MW 2,000

100, 250 & 500mg

Propargyl-PEG-Mal, MW 2,000 is a linear heterobifunctional PEG derivative which can undergo click

chemistry with an azide molecule in the presence of copper catalyst. The polymer is reactive with thiol

molecule or cysteine to from a stable thioether bond.

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BP-25841

Propargyl-PEG-Mal, MW 3,400

100, 250 & 500mg

Propargyl-PEG-Mal, MW 3,400 is a thiol reactive polyPEG. The alkyne terminal can be reacted with azide

molecule via copper catalyzed click chemistry.

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BP-25842

Propargyl-PEG-Mal, MW 5,000

100, 250 & 500mg

Propargyl-PEG-Mal, MW 5,000 is a linear PEG polymer with terminal alkyne and maleimide. The polymer

can be clicked to azide molecule via CuAAC to form a triazole linkage. The maleimide moiety is reactive

with cystein or other thiol molecule at pH 6.5 to 7.5.

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Bis-Propargyl-PEG

BP-25843

Bis-propargyl-PEG, MW 1,000

500mg, 1g & 5g

Bis-propargyl-PEG, MW 1,000 is a linear homobinfunctional polyPEG for crosslinking with azide molecules

via copper catalyzed azide-alkyne cycloaddition (CuAAC).

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BP-26131

Bis-propargyl-PEG, MW 2,000 

500mg, 1g & 5g

Bis-propargyl-PEG, MW 2,000 is a homobifunctional PEG polymer with terminal alkyne. The polymer is a

click chemistry reagent which can react with azide molecules in the presence of copper catalyst to form

stable triazole bonds. 

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BP-25846

Bis-propargyl-PEG, MW 5,000

500mg, 1g & 5g

Bis-propargyl-PEG, MW 5,000 is an azide reactive PEG polymer. The polymer undergoes click chemistry

with azide to form a stable trizole bond in the presence of copper catalyst.

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m-PEG-Propargyl

BP-25848

m-PEG-Propargyl, MW 1,000

500mg, 1g & 5g

m-PEG-Propargyl, MW 1,000 is a click chemistry PEG reagent. The reaction between an alkyne and azide

can be done via copper catalyzed azide-alkyne cycloaddition (CuAAC) to yield a stable triazole bond.

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BP-25849

m-PEG-Propargyl, MW 3,400

Inquire

m-PEG-Propargyl, MW 3,400 is a linear PEG polymer with terminal alkyne for click chemistry with azide

molecule.

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BP-25851

m-PEG-Propargyl, MW 10,000  

500mg, 1g & 5g

m-PEG-Propargyl, MW 10,000 is an azide reactive click reagent. The reaction between alkyne and azide

forms a stable triazole bond.

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BP-25852

m-PEG-Propargyl, MW 20,000

500mg, 1g & 5g

m-PEG-Propargyl, MW 20,000 can be used for click chemistry with azide molecule in the presence of

copper catalyst. The click reaction forms a stable triazole bond.

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BP-25847

m-PEG-Propargyl, MW 2,000

Inquire

m-PEG-Propargyl, MW 2,000 is an alkyne functionalized PEG derivative. The alkyne is reactive with azide

molecule in the presence of copper catalyst to form a triazole linkage.

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BP-25850

m-PEG-Propargyl, MW 5,000

Inquire

m-PEG-Propargyl, MW 5,000 is a monofunctional PEG derivative with terminal alkyne for click chemistry

with azide in the presence of copper catalyst.

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Amine Alkyne-PEG-OH

BP-25816

Amine Alkyne-PEG-OH, MW 2,000

100, 250, 500mg & 1g

Amine Alkyne-PEG-OH, MW 2,000 is a PEG polymer derivative with three reactive sites. The polymer is

used for coupling with NHS ester. It is also azide reactive to form a stable triazole bond. The hydroxyl group

can further derivatize to other molecule.

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BP-25817

Amine Alkyne-PEG-OH, MW 3,400

100, 250, 500mg & 1g

Amine Alkyne-PEG-OH, MW 3,400 is a succinimidyl (NHS) ester reactive polymer which is reactive with

azide molecule through CuAAC click chemistry to form a triazole linkage.

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BP-25818

Amine Alkyne-PEG-OH, MW 5,000

100, 250, 500mg & 1g

Amine Alkyne-PEG-OH, MW 5,000 is a copper click chemistry polyPEG which is reactive with a

succinimidyl ester to form a covalent amide bond. The hydroxyl group can further derivatize to other

molecule.

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BP-25819

Amine Alkyne-PEG-OH, MW 10,000

100, 250, 500mg & 1g

Amine Alkyne-PEG-OH, MW 10,000 can be coupled with NHS ester to form a stable amide bond. The alkyne

moiety is reactive with azide via copper click chemistry to form a stable triazole bond.

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