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Polymer PEG (Polydisperse PEG)
Polymer PEG is a Polyethylene glycol (PEG) polymer with an averaged molecular weight, such as 2K, 5K,
10K, 20K with PDI ranging from 1.01-1.10. Polymer PEG is also known as polydisperse PEG, or Poly-PEG.
There are different shapes of Polymer PEG, such as linear, Y-shaped, branched, or star shaped with
different PEG chain lengths as shown in Figure 1. PEG chain can be attached with different functional groups
for chemistry modification and industrial application.
Figure 1. Examples of Polymer PEG that are commercially available. Typical functional groups include
Acrylate, alkyne, Amine, Azide, DBCO, TCO, Aldehyde, Acid, NHS ester, Hydrazide, Maleimide, Silane,
Biotin, Tos, or Thiol.
Polymer PEG have become especially attractive tools in various pharmaceutical, biological and chemical
industry application due to its aqueous solubility, high flexibility and non-immunogenicity
Polymer PEG, Aldehyde
Aldehyde-terminated polyPEG can react with N-terminal of peptide/protein or amino molecule via Schiff base
reaction to yield an imine bond.
m-PEG-Propionaldehyde
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Catalog No.
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Product Name
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Size
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Feature
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Structure
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BP-25285
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m-PEG-Propionaldehyde, MW 5,000
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1g & 5g
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m-PEG-Propionaldehyde, MW 5,000 is an aldehyde PEGylation reagent which is reactive with hydrazide or
aminooxy groups for biomolecular probes and labeling. The hydrophilic PEG chain increases the water
solubility of the compound in aqueous media.
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BP-25282
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m-PEG-Propionaldehyde, MW 20,000
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1g & 5g
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m-PEG-Propionaldehyde, MW 20,000 is an aldhehyde functionalized PEG polymer. Propionaldehyde reacts
with hydrazide or aminooxy compound to form a hydrazone bond and an oxime bond respectively.
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m-PEG-Butyraldehyde
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BP-25263
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m-PEG-Butyraldehyde, MW 2,000
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1g & 5g
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m-PEG-Butyraldehyde, MW 2,000 is an aldhehyde functionalized polyPEG. Butyraldehyde reacts with
hydrazide to form a stable hydrazone linkage or with alkoxyamines to form a stable oxime bond. The
hydrophilic PEG chain increases the water solubility of the compound in aqueous media.
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BP-23396
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m-PEG-Butyraldehyde, MW 5,000
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500mg & 1g
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m-PEG-Butyraldehyde, MW 5,000 is a PEG polymer with an aldehyde which is reactive with hydrazide or
aminooxy groups for biomolecular probes and labeling. The hydrophilic PEG chain increases the water
solubility of the compound in aqueous media.
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BP-25261
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m-PEG-Butyraldehyde, MW 10,000
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1g & 5g
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m-PEG-Butyraldehyde, MW 10,000 is a PEG polymer with an aldehyde end group which is commonly used
in PEGylation process due to its reactivity with hydrazide or terminal amine of proteins, antibodies,
hormones, and polypetides.
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BP-25262
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m-PEG-Butyraldehyde, MW 20,000
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1g & 5g
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m-PEG-Butyraldehyde, MW 20,000 is a PEG polymer with an aldehyde moiety which enables reaction with
hydrazide forming hydrazone bond and with N-terminal of proteins to form an imine bond in bioconjugation
processes.
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BP-25264
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m-PEG-Butyraldehyde, MW 30,000
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1g & 5g
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m-PEG-Butyraldehyde, MW 30,000 is an aldehyde PEG polymer which is reactive with hydrazide or amine
to form a hydrazone or imine bond respectively. The hydrophilic PEG chain increases the water solubility of
the compound in aqueous media.
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PEG-bis-Butyraldehyde
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BP-25299
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PEG-bis-Butyraldehyde, MW 3,400
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1g & 5g
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PEG-bis-Butyraldehyde, MW 3,400 is a PEG polymer with two aldehyde groups and is reactive with
hydrazide or amine group to form a stable hydrazone or imine bond respectively.DSPE-PEG-Ald, MW 1,000
is a PEG polymer with hydrophilic phosphate head and hydrophobic lipid tails. The polymer can self-
assemble to form lipid bilayer in water. The phospholipid polyPEG can be used as a drug nanocarrier for
administration of nutrients and therapeutic drugs, such as liposome in mRNA or DNA vaccines. The
aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a
reversible imine bond.
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DSPE-PEG-Aldehyde
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BP-26183
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DSPE-PEG-Ald, MW 1,000
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100, 250 & 500mg
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DSPE-PEG-Ald, MW 1,000 is a PEG polymer with hydrophilic phosphate head and hydrophobic lipid tails.
The polymer can self-assemble to form lipid bilayer in water. The phospholipid polyPEG can be used as a
drug nanocarrier for administration of nutrients and therapeutic drugs, such as liposome in mRNA or DNA
vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to
form a reversible imine bond.
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BP-26184
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DSPE-PEG-Ald, MW 2,000
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100, 250 & 500mg
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DSPE-PEG-Ald, MW 2,000 is a phospholipid polyPEG which can self-assemble to form lipid bilayer in
aqueous solution. The polymer can be used to prepare liposome as a drug delivery vehicle for
administration of drugs or nutrients, such as mRNA vaccines. The aldehyde is reactive with aminooxy to
form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond.
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BP-26185
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DSPE-PEG-Ald, MW 3,400
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100, 250 & 500mg
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DSPE-PEG-Ald, MW 3,400 is a self-assemble polyPEG which spontaneously forms lipid bilayer in water.
The polymer can be used to prepare nanoparticles or liposomse as a targeted drug carrier, such as mRNA
vaccine. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to
form a reversible imine bond.
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BP-26186
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DSPE-PEG-Ald, MW 5,000
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100, 250 & 500mg
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DSPE-PEG-Ald, MW 5,000 is a phospholipid PEG polymer which can self-assemble spontaneously in water
with their hydrophilic heads oriented toward the water (micelles). The polymer can be used to prepare
liposome as a drug nanocarrier for administration of nutrients and therapeutic drugs, such as lipid
nanoparticles in mRNA or DNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime
linkage or with amine at pH < 7 to form a reversible imine bond.
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4 arm-PEG-Propionaldehyde
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BP-25169
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4 arm-PEG-Propionaldehyde, MW 10,000
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1, 2 & 5g
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4 arm-PEG-Propionaldehyde, MW 10,000 is a multiarm PEG polymer with four terminal aldehydes which is
reactive to hydrazide and aminooxy to form hydrazone bond and oxime bond respectively.
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