NuGel™ / Polymer Coated Silica Affinity Matrices
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NuGel™ / Polymer Coated Silica Affinity Matrices
독자적인 폴리머 코팅 기술에 의해 비특이적 결합 부위를 없애고 효과적인 affinity 정제를 가능하게 한 실리카 겔 매트릭스입니다. Ligands를 고정하여 사용하는 제품과 ligands 고정화 된 제품이 있습니다.
- Silica 겔을 폴리머로 코팅하여, 비특이적 결합 부위를 거의 완전하게 없앴습니다.
- LC 및 batch processes을 이용한 affinity 정제에 유용합니다.
- Silica 겔이 반응성 Poly-Epoxy기와 안정된 가교를 형성하고 있기 때문에, 넓은 pH 범위 (2 ~ 10)에서 안정적입니다.
- 넓은 용매 호환성을 가지고 있습니다.
- 1000Å, 50µm Silica suitable for LC and batch processes
Silica has been an industry standard as an advantageous matrix suitable for high performance liquid chromatography. With NuGel™, non-specific sites have been virtually eliminated making it an ideal
support for affinity purification. Through a proprietary polymer coating, Silica is crosslinked forming a reactive Poly-Epoxy functionality stable across a wide pH range (pH 2 to 10). From this foundational
chemistry, all of the NuGel™ affinity products are derived.
NuGel™ Poly-NHS Technical Data
NuGel™ Poly-NHS is a derivative of NuGel™ polyamino affinity support. This affinity support contains NHS groups at the end of hydrophilic spacer arms and is used to couple ligands containing amino
groups.
Technical Data
|
Spacer Arm |
Polymerized hydrophilic carbon chain |
|
Porosity |
1000Å |
|
Average Particle Size |
50um |
|
Substitution Level |
100-200 uEq/gm of NHS groups |
Applications : Enzyme immobilization, separation and purification of biopolymers, immobilization of proteins & ligands – monoclonal antibodies, hormones, peptides, haptens, drugs, etc
Product Sheet (PDF)
Ordering informations ;
|
For Immobilization
of Proteins, Antibodies, Hormones, Peptides, Haptens, Drugs, Etc. | ||||
|
Catalog No. |
Product Name |
Matrix Reactive Group |
Ligand Reactive
Group |
Special Features |
|
NPEY-25 |
NuGelTM Poly-
Epoxy |
Terminal Epoxy |
Amino |
Direct Coupling of Amino Groups |
|
NPAM-25 |
NuGelTM Poly-
Amine |
Terminal Amine |
Carboxylic Acid,
or Carbohydrate |
Carbodiiamide reaction, or
NaIO4 derived Aldehyde |
|
NPAY-25 |
NuGelTM Poly-
Aldehyde |
Terminal Aldehyde |
Amino |
Direct Coupling of Amino Groups |
|
NPHX-25 |
NuGelTM Poly-
Hydroxy |
Terminal Glycol |
Amino |
Carbodiimidazole mediated reaction |
|
NPCY-25 |
NuGelTM Poly-
Carboxy |
Terminal Carboxylic
Acid |
Amino |
Carbodiiamide mediated reaction |
|
NPNS-25 |
NuGelTM Poly-
NHS |
Terminal N-Hydroxy
Succinimide |
Amino |
Direct Coupling of Amino Groups |
* Size ; 25 grams,
* Column Volume approximately ; 50 ml
* Kilogram quantities and other particle sizes and porosity of NuGelTM are also available upon request.
* 고정화된 제품은 별도로 문의하여 주시기 바랍니다.
▣ 관련 페이지 ; Biotech Support Group
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