Penicillin Drug Stability Test Kit
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Penicillin Drug Stability Test Kit
가수분해된 페니실린을 검출하는 키트
Penicillin Drug Stability
Penicillin drugs such as Penicillin G and Penicillin V can be hydrolyzed to form penicilloic acid during storage or
transportation due to various reasons including the following: (1) the temperature is too high; (2) the solution pH is
not optimal for stabilization; or (3) the sample contains lactamase. The hydrolyzed penicillin drug molecule is
thermodynamically more stable than the non-hydrolyzed one but completely inactive.
(Penicillin Ⅴ stability test)
A : Frozen sample
B : Heated at 70 ℃, 12 hours
C : RT, 2 days
D : RT with lactamase, 2 days
E : Lactamase only
F : Buffer only
특징
- 페니실린의 가수분해를 신속하게 검출 할 수 있습니다.
- 페니실린을 기질로 하여 lactamase의 활성을 측정 할 수 있습니다.
- 가수분해 되지 않은 페니실린의 back ground는 매우 낮게 억제되어 있습니다.
- 키트에는 96 well plate 또는 마이크로 큐벳으로 100회 분석에 필요한 시약이 포함되어 있습니다.
- 측정 파장 : 여기 485 nm / 형광 535 nm
The Penicillin Drug Stability Test Kit (Catalog number PST100) provides a reagent that quickly detects the hydrolyzed
form of penicillin drugs including the commonly used Penicillin G and Penicillin V. The reagent, Dye PST, interacts with
alpha-amino acids which are the hydrolysis products of penicillin drugs and generates fluorescence at 535 nm with
excitation wavelength at 485 nm. The background signal with the non-hydrolyzed penicillin drugs is very low.
The kit can be used to detect hydrolysis of penicillin drugs. It can also be used to detect the lactamase activity using
penicillin as a substrate.
Each kit (Catalog number PST100) contains 0.5 ml of the 10 x PST dye for 100 assays using 96-well plates or
micro-cuvettes.
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