Hemoglobin Depletion From Hemolyzed Serum/Plasma
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HemogloBind™ Hemoglobin Depletion From Hemolyzed Serum/Plasma
HemogloBind™ Hemoglobin Removal and Capture
많은 전하를 지닌 탄성중합체의 표면에 단백질이 결합하는 성질을 이용한 헤모글로빈 제거용 시약입니다. 시약을 추가하여 간단한 작업 만으로 정제가 완료됩니다. 또한 시료에 따라 시약의 양을 조절
할 수 있기 때문에 경제적입니다. 헤모글로빈에 대하여 높은 특이성을 보여, 혈청 성분과 반응하지 않으며, Thalassemia 등의 헤모글로빈 변종을 식별 할 수 있습니다. HemogloBind에 결합한 헤모글로빈은
pH 조건을 변화시킴으로써 회수 할 수 있습니다.
Features ;
- Has a high degree of specificity for hemoglobin binding up to 10 mg/ml
- Applications in blood substitutes, enzyme recovery and analytical interferences
- Removes hemoglobin from any species including human, sheep, bovine, goat, etc
- Removes hemoglobin from organs, tissues.
- Hemoglobin removal from red blood cell lysate for proteomics and biomarker drug discovery
- The flow through fractions retain their enzymatic and biological activity
- The flow through fractions is compatible with LC-MS, activity based protein profiling and proteomic studies.
HemogloBind™ comes from a class of solid-phase, or surface-based, elastomeric poly-electrolytic surfaces that bind proteins through an mpirically derived chemistry combining elements of polymer
composition, cross-linking architecture and charge properties. HemogloBind™ is engineered for a high degree of selectivity and does not cross react with most common serum components, making it an
excellent tool in numerous applications. These include analytical protocols where optical interference is problematic, such as bilirubin analysis and bulk serum clarification. Hemoglobin variants, as in
thalassemia, bind with differential affinity towards HemogloBind™. For purification and/or analysis of hemoglobin, a modest elevation in pH will facilitate desorption of hemoglobin bound to
HemogloBind™
Ordering informations ;
|
Catalog No. |
Product Name |
Size |
|
HO145-15 |
HemogloBind™ |
15 ml |
|
HO145-50 |
HemogloBind™ |
50 ml |
▣ 관련 페이지 ; Biotech Support Group
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